Autism Genome-wide Scans

• International Molecular Genetic Study of Autism Consortium
  • International Molecular Genetic Study of Autism Consortium. A full genome screen for autism with evidence for linkage to a region on chromosome 7q. Human Molecular Genetics 1998,7:571-578
  • International Molecular Genetic Study of Autism Consortium. Further characterization of the autism susceptibility locus AUTS1 on chromosome 7q. Human Molecular Genetics 2001,10:973-982
  • International Molecular Genetic Study of Autism Consortium. A genomewide screen for autism: Strong evidence for linkage to Chromosomes 2q, 7q, and 16p. American Journal of Human Genetics 2001,69:570-581
• Other studies of 2q linkage region in autism
  • Buxbaum et al. Evidence for a susceptibility gene for autism on chromosome 2 and for genetic heterogeneity. American Journal of Human Genetics 2001,68:1514-1520
  • Shao Y et al. Phenotypic homogeneity provides increased support for linkage on chromosome 2 in autistic disorder. Am J Hum Genet 2002,70:1058-1061
• Other studies of 7q linkage region in autism
  • Ashley-Koch, Wolpert et al. Genetic studies of autistic disorder and chromosome 7. Genomics 1999,61:227-236
  • Collaborative Linkage Study of Autism (CLSA). Incorporating language phenotypes strengthens evidence of linkage to autism. Am J Med Genet (Neuropsychiatric Genetics) 2001, 105:539-547
  • Badner J, Gershon E. Regional meta-analysis of published data supports linkage of autism with markers on chromosome 7. Molecular Psychiatry 2002,7:56-66
  • Alarcón M, ...AGRE... Evidence for a language quantitative trait locus on chromosome 7q in multiplex autism families. American Journal of Human Genetics 2002,70:60-71
• Other genome-wide screens in autism:
  • Paris Autism Research International Sibpair Study. Genome-wide scan for autism susceptibility genes. Human Molecular Genetics 1999,8:805-812
  • Risch, Spiker et al. A genomic screen of autism: Evidence for a multilocus etiology. American Journal of Human Genetics 1999,65:493-507
  • Collaborative Linkage Study of Autism (CLSA). An autosomal genomic screen for autism. American Journal of Medical Genetics (Neuropsychiatric Genetics) 1999,88:609-615
  • Buxbaum et al. Evidence for a susceptibility gene for autism on chromosome 2 and for genetic heterogeneity. American Journal of Human Genetics 2001,68:1514-1520
  • Liu...AGRE... et al. A genomewide screen for autism susceptibility loci. American Journal of Human Genetics 2001,69:327-340
  • New Yonan et al. (AGRE) A genomewide screen of 345 families for autism-susceptibility loci. American Journal of Human Genetics 2003,73:online
  • Shao Y et al. Genomic screen and follow-up analysis for autistic disorder. American Journal of Medical Genetics (Neuropsychiatric Genetics) 2002,114:99-105
  • Auranen et al. A genomewide screen for autism-spectrum disorders: Evidence for a major susceptibility locus on chromosome 3q25-27. American Journal of Human Genetics 2002,71:777-790

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